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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708bd705a2f506d3d9e60d24902f433bf0f7a15be5300cfcd45647d2eb27cc60' 
  AND token = '3P52jaB/YJiGPTRyIRcTRvHTUFqDjA0lZHx8SoZZtOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}