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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297f4f4676c08fe6141715e1c0e8edd1f731dba3d3735158c1d54bd2c0c50293' 
  AND token = 'X0b4dOkH0lO8Dc7Cko+25dty7gbN00/ZONug80glcTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}