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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05c6a77e8895a37a563add2da107636ecc18b064c2c36d2d6b2471aeea7c727' 
  AND token = 'VVpwpP8LugMsJW29Lga80Kjz2kGqqglKUSq5n9YGok0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}