SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535f5983c32768848bae5944e8da874ebb36cdc7c52174485187315a82b1e6a0' 
  AND token = 'ra+IBl7trYKLwApnoJxQfZA6EOcxVKciEgmeHbAFTtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}