SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b95fa432cf639fde021e67cfa537664b9f4cdd9f069a98860369c4581a8952' 
  AND token = 'bX3G5Vx2I3R+m9CJSJwt/AVAo408bLSShxaN1Li3FLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}