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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af409377f055cb3aabd138397ffc613cd65527311efcbbe12d067c40d7a2addb' 
  AND token = 'rssdUsk+46Z7wMAUE+iL5hrRmqiS1Ioh8E51RupvuwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}