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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0408011f3923b54b34ae4030e200d2fb56d2c222660ab066b2a36b87869c0af7' 
  AND token = 'Vmob+U9r644Z1+AW6GzBZhEV8/8taQeCbVc4CX0ginA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}