SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a734da19185f4f9504fad37e3a9ae6752c6c8b8cb3a695141702c150cabde8' 
  AND token = '9z4nUJILguL/+uASE3P7AWo5RBIwyCJ9oE0/UPPTnmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}