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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abcc40a86cb18cb76c744704c6a6956cd0072c0f326f3e6e1c3e2b31266c08f' 
  AND token = 'u6bZxshtogl8wFLC8VxEzUvxJKDw+Ws2X3/sH6bdP+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}