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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d385973735c7ab2e4a433902f6601d7a1982c441c5960c018ee3415cd1cdda' 
  AND token = '5ONujxBVKEJYkCaDYzRWfAKyh0IBJkaeKzxouNuhqF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}