SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0124be0695baddcd9698500cc68f8c261775547c2250d40a10c9bb97afca25' 
  AND token = 'bfF9c+/Napgk9m8niM2otrfSUdlhRvL3PEvEiMNwJ7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}