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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380281d60d663cf2f740a80880d935b6753a2cf13051a4f91709d830a9157c09' 
  AND token = 'l3Gr/v59XFbj/DIXYH3ALudqGkUQTrmtrOH9NvYCJ84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}