SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59a4a0aa742a877c4561897ac044e076695ca2e90f87dcd221c14f661cf2e8f' 
  AND token = 'lD+ttVdFsAg/m8mHxHnv3jn2hhsKY238gOrsf+EvVuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}