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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fcdbc80c39364dc514c9a473b737d71d18e87e78ab5bf8ac6f061ce93288eb' 
  AND token = 'Kz/+wdniMcvh5c62nDOxBJaBkYRRT2j37+Y076Jbakw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}