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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d1b4b8ebda49a3247680b14ae0cea09fe18d7195b3211e5f44c8778bb62d49' 
  AND token = 'BrmQsENvE6yNveVGWSfm7ob2c0IWoCjVZlXtlA9L+Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}