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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd9f78b02ad899f9d51399e21000ef74b5b1ad2c6964054a255431f27f3c63c' 
  AND token = 'WMMolLNUR4RGibPbg2TwKm61em6WSYtZmwgmuUEhRMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}