SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5cbb0f388b818044f5a9995143ec0aab83b87bb9088dde9f3892c4d4099b68' 
  AND token = 'PxEqhi/A1PTrVJrEUyUWw+ceW2Dn0dUli3PPuGrQTz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}