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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f58158c7125fa9986e4dcc11494f3248d0ae06757ad3eae2f936186abae36e' 
  AND token = 'DIjhrGHF0H1pFdS/iWIS3e8VvkFf3KqyL79tL6Nhtvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}