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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1464891287a3d6c78914191a6a69c290f42674d5516be075ab42c3984b99500e' 
  AND token = 'QsdJyjPH2BbfNiRMA1KBFC/GdL4ZMQXpczeePp3Sb7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}