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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a52618e6db995c073fdea6fe5187d854e83391cf3ef87b6f05063cdb2419e7' 
  AND token = 'OM3Iq/1hTD7cz2/FX0agaalfA3r+eMTKd38Ef6zKnNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}