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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b465ab0d75c1bb9b9a4982af38445b306c88eba9c9b1310f06f91ceeca4c4ee2' 
  AND token = 'TPVsojc4xgMwXf5AFxRhDZNa+enb3C3+btmqMMaJ2XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}