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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b519be0f3704fe6a7a125551ae5555e57d0f6f78bdc85063e377206f8ff3dd2' 
  AND token = 'W8Mi1fLtuiw06d6KMwsrRk233dMBzv5Kz9zT2bUOXHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}