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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53c48c99eaef04278990662cfc237080e95a57d11cf8c88f84387fb7ca3dbcb' 
  AND token = 'trwpAjuJnUt/bmvfZyu4TT025VCv93cBYCzm40gRWMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}