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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be51bc8a40f940c9b2ec35944dfce73a022d1a04af1fc9d02108d03da8c8ac1' 
  AND token = 'qZPVSZ4moU/EKPFz/pdmvI0Dq0Q2rfQ64gd1GUF5ZHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}