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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '995f49b351325208c60e2fce2b6dd635e0be395872b513731c4899847e6cc2aa' 
  AND token = '4zYdh7qLuXQNyv4f+/HARf64tgEaaWS+O6yn9EdiEr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}