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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c053d7e7dcbada940b11fa43250294afce9209e461ec1c180bc12c9ec4fdbf58' 
  AND token = 'W9r9OzsKoOHAa4ZM+IJojonAKf/XR+kTuD2gc7MoT2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}