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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e292538a77e1789f8e93bac4a6a768e3ccbcb81d9378d922c4b711eefff4b5' 
  AND token = 'xSuJe59idhNgq3gn3bBM2Um3UH21XM6KSB9kbG2Xqgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}