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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '093c6967406604d2c7b8405de7728e6e22e40e01cfca0663cbfa63981761721f' 
  AND token = 'tkO+3BulzCMDWwZT057ES4gt2HOu+/5B7J6ZR2z82Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}