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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6666aa59b71e454dc306a02ea86a64cd1b9fbd4c7fb1a74604e39ca00ba2c697' 
  AND token = 'vNkdWlJsktSWIrVQK49gjiL/NmzT/bZxCpHjk9Zi5JI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}