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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec37af9b1c49fc1a9e34f25dbcee7afb2e44c1c9b5930b8348c238535638266d' 
  AND token = 'zyO3mccnQGGW7gcB0PSXX5MYRMwTg4rRW5RQFel3oQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}