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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9b1e60b90eec606c302c0817005289dd5ea14d0bf3f28ab7f658f5c22abe52' 
  AND token = 'kbU9GKkVw5Mu+sG3373oZQLc0A0oRkgjkIFvVxlPTaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}