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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f100f3a5ad652802f5240e663ccb461b039d5d5aaa8adf12a10b5f06d61872b' 
  AND token = 'uQ1CD9QQk0TXU8nS4QX5WrpIwEktKwwm4ekFtCfdFqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}