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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f5ca45d98cdb9d3a873e961c756f8e16061f3533345ad28a5adda121f6b17b' 
  AND token = 'LuWWFh1BMclndsMJuCMETnwySwU2oaGTf4nEErVm0SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}