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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fe09ad8e8bed84eaceb1be3acb6c175a754aa38a48275ea2a3b7c53e3afc3f1' 
  AND token = 'ClBVEjv3qBK55SDDds6dvsxPDMDmfzuiESQs3/MSWq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}