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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b17becd7cc2b5b3adf3ffe7ed32018fd646bb9e900358a4f137d4de4153700e' 
  AND token = 'Znq21C+5u/nkVFIa/c8v29guFOHm5vXn2gH9hthshos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}