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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def3d102270b729000fd09a953285cfd8e2d4aff0768558fe5cb961fd1605cb6' 
  AND token = 'pJADZEk7d5qQI3TWHYE6fN0y+X3gqFUIBX50oeIqGEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}