SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e87fe02be1a3feff0f8bad1ff0b9612f4e31d57a74e73a434ee3ea24d125ab' 
  AND token = 'nUXoJzb/BjTNZjPziBTS9h6Qzb7AZogiSswWwnn4pYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}