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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b08b48adeafe1893c4d5aed1a860dccad7cca8dee4dd97af7370025af4df99b' 
  AND token = 'z1FNE10SQp1BnJHqxoq9XwNfsN07i15g9XZPVkJTf5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}