SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5269df0414c2eebab71b42e41d8fbb5208d8ff32dcdbbc1b8b55f3bddc0d33a' 
  AND token = 'G5EeEv5v1ucw+51Sc7Cu+0JB51JcxCFT1FqKJm8eYLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}