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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f379c7d522dfb094e4235b7de720aeb26764443bcbdad22c7420efeada198d' 
  AND token = 'jN0T51AWBqSYDwuv3xVz17KqodgJiD36o8BidZIKa/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}