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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26af5cb9f32188c04b453fa087d8aa2b438327f1b21363f986adc54e55f1c641' 
  AND token = 'SpV5lrnkt4pFP4NuP0PZ6SbmeNOwh1zv6AcgB78ToFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}