SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180710b972b52fbafef14acd9d74581d4911323c9f153e1c3d92d453a060891d' 
  AND token = 'RJD6bhxspWM1o8lbpAI1NN/6Li44K7SjUFQuvAPFKRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}