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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67be69c55d754412073e2f9cd57060a2df8b84d65b8f9080f53b2ce413df5e60' 
  AND token = 'mqRePldnWTEzZ7bolJdlgrHE6XHLcfsFRw2w/c+Xyns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}