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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3185d292feedc8f8c7be9f0cea48f4796cdc78d57299ee9e8efc624bd08ca6cb' 
  AND token = 'a0adbAo6hD/ltn3KYwN66qONP9NyxhlE7M9ZH7diTWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}