SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90a0cd7c02ed16d7897e7be75a783bff01863dc637c84d3b946669563933b1d2' 
  AND token = 'AYzTi2n6T6Tum156edtDjHyKt15aB5LSr2LNQqYK6wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}