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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9135c20316ed90cda0a1612e33463ba43a4b971252e0e50421ceb8dc14f91fb6' 
  AND token = 'uNKjj2+nPQCR+nJGtNggTeceuSW9BVV8+dkSpbTzLRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}