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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea7d94b91a415c8b62c514c94397ae752d80e7d627fc4ce4c27b14b811ee70' 
  AND token = '9m5sXYLYyLz7ZkMPp3+gOTCPfLHYMZfHungHZj8gXxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}