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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f21818235248804e57202e4b548011782c546d5a8fa0a6a1e76df764905177' 
  AND token = 'qWjB/xA5//qPOulJUythRxgriyr43y3OVXAbzL3nsbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}