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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f691460d3436b7b3e5a1954408fb8c047e748f0786cbc22adb6e6101c27141ff' 
  AND token = 'QOb2VclpmHKYafRm3h/7SSdyE8qxWqd0oXVNv7ANen4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}