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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17b3e5307bd5ae928d7f84c9020bdb8020fbb6caf2c47e734093e523469be48' 
  AND token = 'Ad5s1ugkI7NCtB68MrE7PewymcO1LzLD7dP+MW3vEzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}